DOI: 10.1039/c7lc00468k
Abstract:
The ability to interface microfluidic devices with native complex biological architectures, such as whole organs, has the potential to shift the paradigm for the study and analysis of biological tissue. Here, we show 3D printing can be used to fabricate bio-inspired conformal microfluidic devices that directly interface with the surface of whole organs. Structured-light scanning techniques enabled the 3D topographical matching of microfluidic device geometry to porcine kidney anatomy. Our studies show molecular species are...
Excerpt:
Molecular cluster analysis (i.e., bio-fingerprinting) of microfluidic biopsy samples was conducted using Raman spectroscopy (Desktop H-PeakSeeker; Agiltron) and methodology established in the literature...