DOI: 10.1021/am508123x
Abstract:
Although microfluidic approach is widely used in various point of care diagnostics, its implementation in surface enhanced Raman spectroscopy (SERS)-based detection is challenging. This is because SERS signal depends on plasmonic nanoparticle aggregation induced generation of stable electromagnetic hot spots and in currently available microfluidic platform this condition is difficult to adapt. Here we show that SERS can be adapted using simple paper based microfluidic system where both the plasmonic...
Excerpt:
SERS measurement was performed using an Agiltron R3000 Raman spectrometer with 785 nm excitation laser having 5 mW laser power and 10 s integration time...